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Original Article
Two cases of islet cell hyperplasia with nesidioblastosis.
Myeong Ku Cho, Kyeong Bae Park, Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee, D.H Lee
Clin Exp Pediatr. 1991;34(2):273-280.   Published online February 28, 1991
Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or adenoma. We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was found, but histology revealed islet cell hyperplasia and nesidioblastosis. After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other showed normal glucose...
Two cases of meconium peritonitis.
Hye Kyung Nam, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(2):256-260.   Published online February 28, 1991
Meconium peritonitis is a non-bacterial foreign body and chemical peritonitis occurring during intrauterine or early neonatal life as the result of an abnormal communicatiion between the bowel contents and the peritonesal cavity. We experienced two cases of meconium peritonitis, diagnosed in according to the clinical and radiologic features, in two female neonates who had the chief complaint of vomiting and abdominal distention. A brief review...
Adrenocortical carcinoma in a twelve month old male infant.
Woo Ryoung Lee, Kyoung Whan Oh, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(1):137-143.   Published online January 31, 1991
Adrenocortical carcinoma is a rare disease in childhood. Most of these carcinomas are functional, produc- ing endocrine abnormalities such as Cushing syndrome, virilization, precocious puberty, hyperaldosteronism or feminization. We experienced a case of adrenocortical carcinoma in a 12 month old male infant who exhibited features of Cushing syndrome, Virilization, precocious puberty and hyperaldosteronism, which were due to functional adrenocortical carcinoma. Microscopic examination revealed cellular pleomorphism...
A case of congenital lactic acidosis.
Suk Min Choi, Myeong Ku Cho, Dong Hwan Lee, Sang Jhoo Lee, Kikumaro Aoki, Shuichi Yamaguchi
Clin Exp Pediatr. 1991;34(1):95-100.   Published online January 31, 1991
The congenital lactic acidosis represent a sizable group of metabolic disorders. They are in all likelihood genetically determined, and they are clearly heterogenous. They may be considered broadly as disorders of pyruvate metabolism in which there are two general categories: defects in gluconeogenesis and defects in pyruvate oxidation. We experienced a case of congenital lactic acidosis in neonate who was diagnosed by urinary organic acid...
Clinical Evaluation in Lipoid Pneumonia.
Myeong Ku Cho, Suk Min Choi, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(12):1656-1661.   Published online December 31, 1990
Seven cases of lipoid pneumonia in infant who were admitted to department of pediatrics, Soon Chun Hyang University Hospital from July 1988 to March 1990 were reviewed and analysed. The results were as follows: 1) All cases were taken shark liver oil (squalene®) forcefully in supine position 2) Out of 7, all cases were between the age of 3 months and 6 months, and the male...
A Study on Lighting in school.
Kyung Hwan Oh, Woo Ryung Lee, Sang Cheol Park, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(12):1623-1630.   Published online December 31, 1990
The students had to spend their most of times in school. It was supposed that the lighting of classrooms greatly affected the growth and development and visual acuity of students. The illuminance was measured in 12 classrooms of Chun An city (primary, middle and high school) from July to September, 1989. To evaluate the present status and problems of lighting in classrooms, we analyzed...
A Case of Cloacal Exstrophy.
Kyung Hwan Oh, Joon Soo Park, Hak Joo Cha, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(11):1574-1578.   Published online November 30, 1990
Cloacal exstrophy is a rare congenital anomaly. This anomaly results from failure of cloacal cpntatinn with the persistence of ? into which ilpiiir* and a rndirnAntary hind gut open. We have experienced in a 1-day old male neonate a typical case of cloacal exstrophy associated with omphalocele, genital anomaly, imperforated anus, meningocele, spina bifida, widely separated symphysis and equinovarus. A brief review of related literatures was made.
A Case of Crohn's Disease.
Suk Min Choi, Myeong Ku Cho, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(11):1567-1573.   Published online November 30, 1990
Crohn’s disease is a chronic inflammatory disease, which may affect any area of the gastrontestinal tract from mouth to anus. The etiology is not clearly defined and rather uncertain. The incidence of the disease is geogra- phically unequal in world wide distribution. Male and female are equally involved. We experienced a case of CrohnDisease in 13 year old male child who complained abdominal pain, anorexia...
Cystinurua in Siblings.
Sung Ik Cho, Min Yong Oum, Jae Ock Park, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(3):351-359.   Published online March 31, 1990
We report cystinuria in siblings. Renal colic, hematuria, dysuria and stone passage were developed in younger brother (4 year 6 month old boy). But the elder sister (6 year old girl) had no specific symptoms nor signs. The identification of the disease was proved by cyanide nitroprusside test and amino acid analysis of urine. In our patients the chromatographic amino acid patterns of urine showed...
A Case of Sirenomelia.
Hyun Kuk Kim, Sung Ik Cho, Byoung Tae Kim, Hak Jhoo Cha, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(2):241-245.   Published online February 28, 1990
A neonate weighing 960 gm with undetermined sex was born after 32 weeks of gestation. The baby had multiple abnormalities such as fused lower extremities, abcence of the anus and external genitalia, meningomyelocele, right anortia, anomalous ribs, pulmonary hypoplasia, renal agenesis and rectal agenesis. The diagnosis was established by physical and autopsy findings. A brief review of literature was made.
Glucose-6 Phosphate Dehydrogenase Deficiency.
Meen Jai Lee, Sang Eun Lee, Dong Whan Lee, Sang Jhoo Lee, Sang Chul Park
Clin Exp Pediatr. 1990;33(2):212-219.   Published online February 28, 1990
Glucose-6-phosphate dehydrogenase(G-6PD) deficiency is the most common disease-producing enzyme deficiency of human beings, but extremely rare in Korea. Four well-characterized clinical syndromes are recognized: acute, oxidative stress(drug or infection) induced hemolytic anemia; neonatal hyperbilirubinemia; favism and chronic nonspherocytic hemolytic anemia. We have experi- enced a case of G-6PD deficiency in child associated with chronic hemolytic anemia and exacerba- tions of hemolysis by infection and drug...
A Case of Nonimmunologic Hydrops Fetalis Associated with Down Syndrome.
Sang Eun Lee, Meen Jai Lee, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(2):205-211.   Published online February 28, 1990
We experienced a case of nonimmunologic hydrops fetalis associated with Down syndrome. The patient had generalized edema with severe scrotal swelling and abdominal distension. A roentgenogram showed bilateral pleural effusion and ascites. The chromosomal study revealed 21 trisomy. On autopsy, there were pleural fluid and ascites as well as pericardial fluid. Small ASD and incomplete lobation of the right lung were detected. Chromosomal abnormalities should always...
A Clinical and Diagnostic Study of the Allergic Rhinitis in Children.
Hyun Kuk Kim, Min Yong Oum, Bok Yang Pyun, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(2):189-195.   Published online February 28, 1990
Recently many studies and development of allergology especially in allergic rhinitis have been carried out and the number of allergic rhinitis patients has been increased. In order to get basic clinical information, the authors performed clinical and diagnostic analysis with 132 cases complaining of nasal stuffness, watery rhinorrhea or sneezing who visited the out- patient department of Pediatrics, Soon Chun Hyang University Hospital from...
Statistical Analysis of Death Cases in Pediatric Ward.
Kui Ae Jang, Kyeung Bae Park, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1990;33(1):1-9.   Published online January 31, 1990
Statistical analysis of death cases during the 9 years from Jan. 1979 to Dec. 1987 in pediatric ward of Soonchunhyang university hospital was carried out. The following results were observed. 1) Total numbers of admission during the 9 years were 16365, of whom 296 expired. 2) Average mortality rate was 1.8% and the annual mortality rate showed decreasing tendency from 1979 to 1987. 3) In age distribution, the neonates...
A case of paraquat poisoning in child.
Min Yong Oum, Sung Ik Cho, Young Chang Kim, Hak Ju Cha, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(11):1540-1545.   Published online November 30, 1989
Paraquat is a widely used herbicide and its poisoning in human induces acute renal failure, hepatic dysfunction, progressive respiratory failure, oral cavity ulcer and cardiac manifestations with high mortality rate. We experienced a case of paraquat poisoning in a 12 years old child who revealed acute renal failure, pneumothorax, subcutaneous emphysema, pneumomediastinum and died 44 hours at acciden- tal ingestion of paraquat solution inspite of...
Three Cases of Kawasaki Disease Accompanied with Rare Clinical Menifestation.
Min Yong Oum, Sang Eun Lee, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(9):1300-1308.   Published online September 30, 1989
We experience 3 cases of Kawasaki disease accompanied with rare clinical manifestations. The first case was 6 year old boy who accompanied with hydrops of gallbladder and facial palsy. The second case was 7 month old boy who developed vesicles, crust, and desquamation of the BCG inoculation site. The third case was 18 month old boy who developed transverse groove (Bow’s line) of the...
Current Immune Status of Children and Pregnant Women in Korea(I).
Eun Jung Kim, Ju Kwan Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(5):620-629.   Published online May 31, 1989
This study was conducted to find out rubella immune status as basic data for devising surveillance plan to prevent rubella epidemic and congenital rubella syndrome in Korea. Rubella ELISA antibody was tested to the study group of 253 cord blood. 352 children and 486 pregnant women. who visited Soonchunyhang University Hospital from Feb., 1987 to Oct.. 1987 The provisional results obstanined from the study...
The Precalence and Trend of Obesity in Children and Adolescents.
Kyu Bum Cho, Soon Bok Park, Sang Chul Park, Dong Hwan Lee, Sang Jhoo Lee, Sung Jae Suh
Clin Exp Pediatr. 1989;32(5):597-605.   Published online May 31, 1989
The pose of this study is to survey the prevalence and trend of obesity at ages 6 to 11 in Seoul from 1984 to 1988. The number of children and adolescents comprised of 5,391 boys and 5,289 girls. Overweight was defined as weight that exceeded the standard weight for height and sex by more than 20% (relaive weight > 120%). The result was as...
A Case of Type A Niemann-Pick Disease.
Young Bong Moon, Yang Bin Im, Dong Hwan Lee, Sang Jhoo Lee, In Sook Kim, Tae Jung Kwon, Dong Wha Lee
Clin Exp Pediatr. 1989;32(3):402-411.   Published online March 31, 1989
We experienced a case of type A Niemann-Pick disease in 31 month-old female infant. She showed dyspnea, marked hepatosplenomegaly and developmental retardation. Fundoscopic examination revealed cherry red spots in both macula. Autopsy finding revealed that Iiver, spleen, lung, kidney, bone marrow, lymph node and brain were involved. Especially multiple ischemic necrosis were found on cerebral and cerebellar white matter. Generalized muscular atrophy and reticular...
An Epidemiological Study of Bronchial Asthma in Children Who Visited the Emergency Room.
Ju Kwan park, En Jung Kim, Bok Yang Pyun, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(2):215-222.   Published online February 28, 1989
Presently, an increasing incidence of Bronchial asthma in children is of concern to medical professionals. Worldwide data from surveys indicate a wide range for the prevalence of childhood asthma, it has been estimated that 5-10% of the young population. An epidemiological approach was used to test the prevalence of bronchial asthma out of all pediatric cases referred to the emergency room. 248 cases were selected...
A Case of Neonatal Short Bowel Syndrome.
Gill Hyoun Kim, In Chul Yoo, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(1):81-86.   Published online January 31, 1989
We experienced a case of neonatal short bowel syndrome due to multiple jejuno-ileal atresia with microcolon. On the 1st day of her life, there were symptoms of vomiting and abdominal distension. The radiological study show multiple dilated intestinalloops and malrotation. On the 4th day of her life, the extensive enterectomy was done. The remaining small bowel consisted of 30 cm of proximal jejunum and distal...
Pancreatic ISlet-cell Adenoma in a Neonate.
Kyu Bum Cho, Yang Bin Im, Dong Hwan Lee, Sang Jhoo Lee, Tae Jeong Kwon, Dong Hwa Lee
Clin Exp Pediatr. 1988;31(12):1650-1656.   Published online December 31, 1988
Islet cell adenoma is a rare cause of severe neonatal hypoglycemia. A newborn infant with severe symptomatic hypoglycemia had persistent hypoglycemia in spite of therapy with parenteral glucose solution. Islet-cell adenoma of mixed islet-acinar type was found when subtotal pancreatectomy was performed at 42 days of age. Following surgery she had a transient hyperglycemia and required isulin for 40 days. She has remained normoglycemic but...
Clinical Evaluation of Bleeding Tendency in Childhood.
In Chull Yoo, Gill Hyoun Kim, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1988;31(12):1641-1649.   Published online December 31, 1988
Four hundred and ninety-nine cases of bleeding disorders in childhood who were admitted to department of pediatrics, Soon Chun Hyang University Hospital during 10 years from July 1977 to June 1987 were clinically evaluated. The results obtained were as follows: 1) The incidence of bleeding disorders was 2.97% of total admitted patient. There was no signifi- cant difference in annual incidence. 2) The peak age of incidence was...
Present status and Problems of weaning.
Young Le Yoon, Moon Hae Bang, Hong Kee Bang, Gang Il Lee, Hak Joo Cha, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1988;31(7):863-872.   Published online July 31, 1988
This study was conducted to find out the present status and problems of weaning in the provinces of Korea with the 578 outpatients who visited Chun-An, Ku-Mi and Eum-Sung Soon Chun Hyang University Hospital from November 1986 to June 1987. The results and problems obtained from the study are summerized as follows 1) Among 578 parents of this study, 173 were from country and 405...
Clinical Observation of Human Rota Virus(HRV) Gastroenteritis.
Kee Don Hong, Gil Hyun Kim, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1988;31(6):700-706.   Published online June 30, 1988
This study was done with the 96 patients with watery diarrhea from Oct. to Nov. 1986. ELISA study was done to detect Human Rota Virus antigen for all patients. Clinical and laboratory comparision were made between HRV antigen positive group and HRV antigen negative group. The results were as follows: 1) HRV antigen was detected in 62 patients (64.6%) among 96 patients of diarrhea or...
A Case of Medistinal Lipoma.
Hung Sub Choi, Myung Ho Oh, Chang Hwi Kim, Sang Jhoo Lee, Yong Sik Lee
Clin Exp Pediatr. 1988;31(1):141-146.   Published online January 31, 1988
The mediastinal lipoma is a rare benign tumor. Since the original description by Fothergill in 1781, about 120 cases have been reported in literature. Of these, less than ten have been reported in children below the age of twelve. We experienced a case of mediastinal lipoma, in a 5 year old girl with mild dry cough. Chest X-ray showed a large, homogeneous soft tissue...
A Clinical Studey on Reye Syndrome.
Myung Ho Oh, Hung Sub Choi, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1987;30(11):1243-1251.   Published online November 30, 1987
We took clinical study for 47 cases of Reye syndrome at S.C.H. University Hospital during last 8 years from Jan:, 1979 to Dec., 1986. The results obtained were as follows; 1) There was no significant difference in annual incidence and the seasonal incidence was highest in sumer and autumn. 2) The sex ratio of male to female was...
Diagnosis and Hydrostatic Reduction of 5 Cases of Intussusception Under Ultrasound Guidance.
Hee Kyung Park, Moon Hae Bang, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1987;30(8):901-906.   Published online August 31, 1987
I nt ussuscept i on is the condition of invagination of one part of intestinal loop into the contiguous distal segment. During infancy and early childhood, intussusception is the most common cause of acquired intestinal obstruction, and it requires emergency treatment. Recently, the use of ultrasound as a diagnostic and therapeutic tool of intussusception is now becoming a well-established method because it is simple,...
Present Status and Problems of Weaning.
Hong Kee Pang, Kyoung Hee Kim, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1987;30(3):266-274.   Published online March 31, 1987
This study was conducted to find out the present status and problems of weaning in Korea through the 200 infants who visited Maternal-Child Health Center, Soon Chun Hyang University from Nov. 85 to June 86. The result and problems obtained from the study are summarized as follows: 1) Most of the infants were under 12 month of age(86.5%). 2) Most of the fathers belonged to 30-39...
A Case of Glanzmann's Thromboasthenia.
Hee Kyung Park, Kyung Hee Kim, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1987;30(2):223-228.   Published online February 28, 1987
Glanzmann’s Thromboasthenia is a rare autosomal recessive hemorrhagic disorder characterized by chronic nonthrombocytopenic purpura, a prolonged bleeding time, and deficient or absent clot retraction. The major underlying abnormality is defective first phase aggregation of platelets, which are unresponsive to ADP in any concentration. The authors experienced one case of Glanzmann’s Thromboasthenia in a 8 year 10 month old female, who had frequent epistaxis and gingival...
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